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First Year Chemistry Course Units
CH
1003 Practical Chemistry I (60P,2C, Core)
Dependencies:
None
Syllabus:
Safety
in laboratory, Quantitative analysis, qualitative analysis of organic and
inorganic compounds, Chromatography and simple synthesis.
Duration: First Semester and 5
weeks of second semester.
Assessment: One or more practical
assessments.
Suggested Readings: Quantitative analysis (Vogel),
Quantitative analytical chemistry, Vol. I. Introduction to principles (H.A. Flaschka,
A.J. Barnard and P.E. Sturrock)
CH 1004 Practical
Chemistry
II
(30P,1C, Optional)
Dependencies:
CH 1003 recommended.
Syllabus: Molecular modeling,
Synthesis, spectroscopy.
Assessment: End of semester practical
examination.
Suggested Readings: Hyperchem
– users manual, Organic chemistry (L.G. Wade)
Dependencies:
CH 1008, CH 1009 recommended.
Syllabus:
Polymers:
Organic polymers (polyphenols, polyvinyls),Natural
polymers (proteins, polypeptides, polysaccharides); Petroleum products: Formation, processing, use and
environmental damage; Pesticides and Fertilizers: Synthesis, Chemical
Reactivity and environmental damage, Exposure and health effects;
Pharmaceuticals (drugs): Synthesis,
Activity and dose; Chemical industry: paints, emulsions, colloids, synthetic
materials, soap and detergents, ceramics and cement, Standards and Quality
assurance; Electrochemistry applications: Cells and corrosion, plating,
sensors, fuel cells; Food And Nutrients: Analysis, additives, preservatives.
Assessment: End of semester examination.
Suggested Readings: Will be announced during the
course
CH 1007 Concepts in Biochemistry (for physical students) (15L,1C, Optional)
Dependencies:
CH 1008, CH 1009 recommended.
Syllabus:
Chemical
basis of life: biological fitness of compounds, chemical reactions in living
cells. Special characteristics of living organisms; Bbiomolecules,
the specialization and differentiation of biomolecules;
hormones, pigments, antibiotics, essential oils, lignin; The molecular
organization of cells and cell organelles; Amino acids, peptides and proteins,
the size of protein molecules and structures (Iry,
IIry,IIIry and IVry
structures), denaturation of proteins and
analysis of structure (Edman degradation). Introduction to carbohydrates and
lipids: classification, structure and functional aspects.
Assessment: End of semester examination.
Suggested Readings: Molecular cell biology (H. Lodish et al.), Genes VII (B. Lewin)
CH 1008 General Physical Chemistry
(30L, 2C, Core)
Dependencies: None
Syllabus: Atomic Structure:
nature of light, photoelectric effect, wave particle duality, electromagnetic
spectrum, atomic hydrogen spectrum, the Bohr model of the atom, Heisenberg
uncertainty principle, quantum numbers, orbitals and
their shapes, Pauli exclusion principle, Hund’s rule,
and Aufbau Principle. Introduction to the periodic
table in terms of four quantum numbers, orbital shielding, calculation of the
effective nuclear charge. Introduction to bonding: Types of bonds, radius ratio
rules and coordination numbers, structure of ionic solids, classification of
ionic solids, covalent bonding, Lewis theory, octet rule, dative bonding,
resonance structures, valence bond theory, molecular orbital theory,
application of MO theory to the homo nuclear diatomic molecules, molecular
orbital diagrams for conjugated organic compounds (e.g. ethylene and
butadiene). Chemistry of selected main group elements (e. g. B, P,..etc.), Application of VSEPR method to predict shapes of
organic and inorganic moleculesEnergetics of Chemical
processes: Heat of reactions, Thermal capacities, Kirchoff’s
Equation, The first Law: Heat, Work and Internal energy, State functions and
Path functions, Reversible and Irreversible processes, The second Law:
spontaneous change, Entropy and irreversibility; The three laws of
Thermodynamics, Universal entropy, Gibbs function, Helmholtz function; Phase Equilibria: Clausius Clapeyron equation; Kinetics and Reaction Mechanisms:
Elementary reactions, rates of reactions, order and the rate constant of a reaction,
steady state approximation, rate determining step, Reagents: Radical and polar
reagents: Nucleophiles, Electrophiles,
consecutive, reversible and reactions with equilibrium, competing reactions,
chain reactions. Arrhenius equation, transition state,
intermediates, energy level diagrams (SN1 and SN2),
isotope effects. Catalysis, Introduction to collision theory,
Assessment: End of
semester examination.
Suggested Readings: Elements of
Physical Chemistry (P.W. Atkins), Physical
Chemistry (G.F. Liptrot, J.J. Thompson. G.R. Walker)
CH
1009 Fundamentals of Organic Chemistry (30L, 2C, Core)
Dependencies:
None
Syllabus: Overview of organic chemistry, Functional
groups, Resonance, Constitutional
isomers, Intermolecular forces and
physical properties, Structure and
bonding of alkanes, Conformations of alkanes (ethane, propane, butane and higher alkanes), Conformational stabilities, Sawhorse and Newman projections, Cycloalkanes (cyclopropane, cyclobutane, cyclopentane, cyclohexane and higher cycloalkanes),
Stabilities of cycloalkanes, conformations of cycloalkanes, Substituted cycloalkanes
and cis,trans isomerism, Mono- and di-substituted cylohexanes and
conformational stabilities, Stereoisomerism, chirality
and optical activity, Molecules with one stereocenter
, Molecules with two or more stereo
centers, R,S-configurations, Fisher
Projection formulas, Resolution of enantiomers, (E)
and (Z) isomers, Acids and bases in organic chemistry, Mechanisms of organic
reactions, Alkyl halides, Ionic reactions (Sn1, Sn2, E1 and E2 reactions),
Radical reactions, Chemistry of alcohols and ethers, Structure, synthesis and reactions of alkenes and alkynes, Aldehydes and ketones, Nucleophilic addition to the carbonyl group, Keto -enol tautomers, Carbonyl condensation reactions, Caboxylic acids and their derivatives.
Assessment: End of the semester examination.
Suggested
Readings:
Organic Chemistry (T.W.G. Solomons), Organic Chemistry (T.W.G. Solomons and C.B. Fryhle), Organic Chemistry (J. McMurry),
Organic Chemistry (L.G. Wade Jr.)
CH 1010 Calculations in Chemistry
(15L, 1C, Optional)
Dependencies: None
Syllbus: Review of basic
Mathematics for Chemistry; use of significant figures and error theory;
calculations based on stoichiometry; calculations
based on equilibria (acid-base, buffers, solubility,
etc.), redox reactions, electrochemistry, and
thermodynamics; use of graphs; use of spreadsheets in chemistry, probability
theory, probability distribution.
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Department of Chemistry, Faculty of Science, University of Colombo,
P.O. Box 1490, Colombo 03, Sri Lanka.
Tel : (9411) 2583105-7, Ext.225 Fax : (9411) 2503148, (9411) 2587239
Last Updated October 2011