CH 2002  Inorganic & Analytical Chemistry (30L,2C, Core)

Dependencies: None

Syllabus: Titrimetry: Conditional constants in acid – base , complexometric and redox titrimetry. Feasibility of titrations, selectivity based on thermodynamic and kinetic factors. Titration curves and selection of suitable indicators; Gravimetry and Precipitation Titrations: Coprecipitation, post precipitation and    Precipitation from homogeneous solutions. Mohr method, Volhard method and adsorption, Indicators; Radio Chemistry : Nuclear particles, models of the nuclei,  a, b, and  g radiation, binding energy and mass defect, band of stability, nuclear fission and fusions, nuclear energy, natural radioactivity, applications; Separational methods: Non – aqueous solvents and the principles of solvent extraction and ion-exchange, planar chromatographic methods, paper chromatography and TLC. Gravity columns and elution chromatography; Chemistry  of transition elements: Introduction to coordination complexes, structure and reactivity. Bonding and properties of transition metal complexes. Theories of bonding: Valence Bond Theory, Crystal Field Theory, and Molecular Orbital Theory, Introduction to organometallic compounds of the transition metals.

Assessment: End of semester examination.

Suggested Readings:  Advanced inorganic chemistry (F.A. Cotton and Wilkinson), Concise inorganic chemistry (J.D. Lee), Inorganic chemistry (J.E. Huheey), Fundamentals of analytical chemistry (D.A. Skoog and D.M. West), Text book of quantitative inorganic analysis (A.I. Vogel), Determination of pH: theory and practice (R.G. bates), Analytical chemistry (J.D. Dick), Chemical separations and measurements: theory and practice  (D.G. Peters, J.M. Hayes and G.M. Hieftje), Inorganic Chemistry (D.F. Shriver, P.W. Atkins and C.H. Langford).

CH 2003 Practical Chemistry III  (60L,2C, Core)

Dependencies: CH 1003

Syllabus: Separation of mixtures, identification of compounds by spectroscopy, solvent extraction, synthesis of organic and organo-metallic compounds, solubility products, potentiometry, spectroscopy.

Duration: First Semester and 5 weeks of second semester.

Assessment: End of semester practical examination.

Suggested Readings: Text book of quantitative inorganic analysis (A.I. Vogel).

CH 2004 Practical Chemistry IV  (30L,1C, Optional)

Dependencies: CH 1003 recommended.

Syllabus: Structure elucidation of organic compound, quantum mechanical calculations, Ion exchange and conductivity.

Duration: Last 10 weeks of second semester.

Assessment: End of semester examination.

Suggested Readings: Text book of quantitative inorganic analysis (A.I. Vogel).

CH 2006 Chemistry of air, water and soil   (30L,2C, Core)

Dependencies: CH 1008 recommended.

Syllabus: Chemistry of Air: Chemical composition of the atmosphere, Effect of solar radiation on atmospheric constituents, Temperature inversions at different altitudes of the atmosphere, Atmospheric pollution, Green House Effects, Global Warming, Acid Rain, London smog, Los Angeles smog, Airborne pollutants and their possible impacts on air quality in Colombo, Ozone Layer Depletion, Impact of air pollution on the society, Sampling and analysis of airborne pollutants, indoor air quality; Chemistry of Water: Hydrosphere, Composition of the hydrosphere, Structure of H₂O and the properties. Chemical equilibria between atmosphere and hydrosphere. Sampling of water. Water purification, Water quality parameters. Suitability of potable waters. Suitability of water for irrigation. Industrial use of water. Re-use of water; Chemistry of Soil: Soil composition, structure of soil, its properties, transport of water through soil, ion exchange properties of soil, minerals, humic and fulvic acids, soil analysis, solid waste and contaminated soil, soil remediation. 

Assessment: End of semester examination.

Suggested Readings: Methods for chemical analysis of fresh water (H.L. Golterman), The hydrogeochemical Atlas of Sri Lanka (C.B. Dissanayake, S.V.R. Weerasooriya), Environmental Chemistry (R.D. Raiswell, R.D. P. Brimblecombe and P.S. Liss), Text book of quantitative inorganic analysis (A.I. Vogel), Determination of pH: theory and practice (R.G. bates), Analytical chemistry (J.D. Dick), Chemical separations and measurements: theory and practice (D.G. Peters, J.M. Hayes and G.M. Hieftje).

CH 2007 Concepts in Molecular Biology (for physical students) (15L,1C, Optional)

Dependencies: None

Syllabus: Nucleic acids: General structure of nucleotides, Pyrimidines and purines, Nucleosides and nucleotides, Nucleic acids (DNA and RNA). Physical and chemical properties of nucleic acids. Hydrolysis of nucleic acids by acids and bases, Enzymatic hydrolysis; The flow of genetic information: Mechanism of replication, Structural constrains and adaptations, Repair systems; Light dependent and light independent pathways (Excision repair, SOS responses, homologous recombination); Tools in Molecular biology: Microorganisms; Geno types and pheno types, advantages of microorganism in molecular biology experiments, Enzymes;DNA polymerases, Restriction endonucleases, Topoisomerases, DNA ligase etc. Molecular Cloning: Cloning vehicles; properties of cloning vehicle, construction of cloning vehicle, Examples of cloning vehicles (phages and plasmids). Isolation of DNA. Cloning methods: southern hybridization, colony hybridization. Screening tools; Enzymatic and immunological techniques.

Assessment: End of semester examination.

Suggested Readings: Molecular cell biology (H. Lodish et.al.), Genes VII  (B. Lewin).

CH 2008 Fundamentals of Physical Chemistry (30L, 2C, Core)

Dependencies: CH 1008 recommended.

 Syllabus: Quantum Chemistry: Failures of Newton’s laws; Operators, Eigen functions and Eigen values, Hermitian operators, Heisenberg Uncertainty Principle, Postulates of quantum mechanics, Schrödinger equation, Born interpretation of the wave function, normalization, orthogonality, particle in a 1-D, 2-D and 3-D boxes, degeneracy. Hydrogen and hydrogen like atoms, spin and angular momentum, atomic units, many body Hamiltonian and the build up of elements, Diatomic molecules and molecular orbitals, introduction to symmetry: Symmetry elements and point groups; Physical Basis of  Spectroscopy: wave and particle nature of matter. Interaction of radiation with matter, energy levels. Absorption and emission of radiation. The basic spectroscopic experiment, Spectrum, Fine structure, population distribution (Boltzmann distribution), selection rules (electronic, rotational, vibrational, NMR), Time scales (uncertainty principle), Basic instrumentation for absorption experiment,  Beer-Lambert law, Electronic spectroscopy of atoms, Electronic spectroscopy (UV/VIS) of molecules, Principles of NMR spectroscopy. Brief introduction to NMR spectroscopy  of ³¹P, ¹⁹F; Molecular Spectroscopy: Vibrations of diatomic molecules, simple harmonic oscillator,  anharmonic oscillator, effect of isotopic substitution, dissociation energy. Rotational spectroscopy: rigid rotor model, intensities of spectral lines, calculation of moment of inertia, internuclear distance for a rigid diatomic molecule, Vibration-rotation spectroscopy, P,Q and R bands, Rotational spectra of non-rigid diatomic molecules; Applications of UV, IR NMR and Mass spectrometry in Organic Structure Elucidation. Electrochemistry: Electrolytes and non electrolytes, conductance, conductivity, molar conductivity, Kohlraush’s law and   Ostwald’s dilution law, limiting ionic conductivity, chain mechanism of H⁺ migration, Debye-Huckel theory of activity, Debye-Huckel limiting law Electrode and cell reactions,  Nernst equation.

Assessment: End of semester examination.

Suggested Readings: Elements of Physical Chemistry  (P.W. Atkins), Physical Chemistry (G.F. Liptrot, J.J. Thompson. G.R. Walker).

CH 2009 Intermediate Organic Chemistry (15L, 1C, Optional)

Dependencies: CH 1009  Fundamentals of Organic Chemistry

 Syllabus: Conjugated dienes and UV spectroscopy; Diels-Alder reaction; aromaticity; aromatic compounds; phenols and aryl halides; amines and anilines; introduction to IR, mass and NMR spectroscopy.

Assessment: End of semester examination.

Suggested Readings: Organic chemistry (L.G. Wade Jr.), Organic chemistry (T.W.G. Solamons).

CH 2010 Phase Equilibria and Surface Chemistry (15L, 1C, Optional)

Dependencies:  CH 1008 recommended.

Syllabus: Definitions of phase, components and degrees of freedom, phase rule, One component, two component and multi component systems. Phase diagrams and phase transitions. Thermodynamics of phase transitions. Surface Chemistry: Interfaces, surface films on liquids, adsorption on solid surfaces, colloids and membranes.

Assessment:  End of semester examination.

Suggested Readings: Physical Chemistry-P.W. Atkins.